Fetal middle-cerebral and umbilical artery flow assessments after glucose challenge test

J. Pardo, R. Orvieto, D. Rabinerson, J. Bar, M. Hod, B. Kaplan

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Objective: To determine whether a change occurs in fetal middle-cerebral and umbilical artery flow after glucose challenge testing. Method: Fetal middle-cerebral and umbilical artery flow was assessed by Color Dopppler technology in 21 pregnant patients before and after the 50-g glucose challenge test. The resistance index (IR) was evaluated separately for each vessel. Statistical significance was determined by Chi-square test and repeated measurement analysis with two co-variates. Results: After glucose ingestion the RI was significantly decreased in the middle-cerebral artery, but not in the umbilical artery. A significant increase in RI was recorded in the umbilical artery when maternal plasma glucose level exceeded 102 mg%. Conclusion: Maternal ingestion of glucose significantly alters blood flow velocimetry in the fetal middle-cerebral and umbilical arteries. These changes may lead to the misinterpretation of normal results. It is therefore recommended that sonographic flow velocimetry assessment not be performed early after concentrated glucose ingestion. Copyright (C) 1999 The International Federation of Gynecology and Obstetrics.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Issue number3
StatePublished - 1 Jun 1999
Externally publishedYes


  • Flow velocimetry
  • GCT
  • Middle-cerebral artery
  • Umbilical artery

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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