Fetal pseudohypoaldosteronism: another cause of hydramnios

D. Greenberg, O. Abramson, M. Phillip

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations


    Pseudohypoaldosteronism (PHA) is a rare hereditary salt–wasting syndrome which is caused by decreased renal tubular responsiveness to aldosterone. The syndrome consists of hyponatremia, hyperkalemia, dehydration, failure to thrive and increased urinary salt loss. A case of PHA was previously described where fetal polyuria was the probable cause of hydramnios. We present four new cases of PHA, from two families, who were born after pregnancies complicated by severe hydramnios and premature labor. We suggest that PHA should be included in the differential diagnosis of hydramnios, since appropriate investigations might lead to the early diagnosis and treatment of a life–threatening disease.

    Original languageEnglish
    Pages (from-to)582-584
    Number of pages3
    JournalActa Paediatrica, International Journal of Paediatrics
    Issue number5
    StatePublished - 1 Jan 1995


    • Hydramnios
    • pseudohypoaldosteronism

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health


    Dive into the research topics of 'Fetal pseudohypoaldosteronism: another cause of hydramnios'. Together they form a unique fingerprint.

    Cite this