TY - JOUR
T1 - Follitropin-α (Gonal-F) versus follitropin-β (Puregon) in controlled ovarian hyperstimulation for in vitro fertilization
T2 - is there any difference?
AU - Orvieto, Raoul
AU - Nahum, Ravit
AU - Rabinson, Jacob
AU - Ashkenazi, Jacob
AU - Anteby, Eyal Y.
AU - Meltcer, Simion
PY - 2009/4/1
Y1 - 2009/4/1
N2 - In an attempt to examine and compare the effect of the two commercially available recombinant FSH on ovarian stimulation characteristics and IVF cycle outcome, we studied 264 IVF cycles in patients with a favorable prognosis a priori, 198 in patients using follitropin-α, and 68 in patients using follitropin-β. Although both groups achieved a comparable number of retrieved oocytes, the use of follitropin-β was associated with a tendency toward a lower clinical pregnancy rate (PR), and with significantly higher E2 levels despite the use of significantly lower total gonadotropin dose.
AB - In an attempt to examine and compare the effect of the two commercially available recombinant FSH on ovarian stimulation characteristics and IVF cycle outcome, we studied 264 IVF cycles in patients with a favorable prognosis a priori, 198 in patients using follitropin-α, and 68 in patients using follitropin-β. Although both groups achieved a comparable number of retrieved oocytes, the use of follitropin-β was associated with a tendency toward a lower clinical pregnancy rate (PR), and with significantly higher E2 levels despite the use of significantly lower total gonadotropin dose.
UR - http://www.scopus.com/inward/record.url?scp=63449106868&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2008.08.112
DO - 10.1016/j.fertnstert.2008.08.112
M3 - Article
AN - SCOPUS:63449106868
SN - 0015-0282
VL - 91
SP - 1522
EP - 1525
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 4 SUPPL.
ER -