TY - JOUR
T1 - Formal thought disorder and psychopathology in pediatric primary generalized and complex partial epilepsy
AU - Caplan, Rochelle
AU - Arbelle, Shoshana
AU - Guthrie, Donald
AU - Komo, Scott
AU - Shields, W. Donald
AU - Hansen, Rebecca
AU - Chayasirisobhon, Sirichai
N1 - Funding Information:
Acupud December6. 1996. Dr. Caplan is Associate Professor; Dr. Arb~lI~ was a research ftllow, Dr. Guthrie is Professor; and Mr. Komo is senior statistician in the UCLA Department ofPsychiatry. Dr.Arbellecurrentlyis Instructor in Psychiatry at th~ Ben Gurion University, Beersheba, Israel. Dr. Shields is Professor and Dr. HansenisAssociate Clinical Proftssor ofPediatricsand N~rology at UCLA. Dr. Chayasirisobhon is Proftssor ofNeurosciences at Charles Drno University, Los Ang~~s. This study was supported in part by NIMH grant KOI-MH00538 and NINDS grant lROINS 32070. w,.aclmowldg~ Amy Mo. Shawn Zink, Natasha Whu~ Kathleen Thompson, and Kevin Bryant for their technical assistance. Reprint "qutSts to Dr. Caplan, Neuropsychiatric Institute, Room 48-253B, 760 w,.stwoodPlaza, LosAng~h CA 90024-1759. 0890-8567/97/3609-1286/$O.300/0© 1997 by me American Academy of Child and Adolescent Psychiatry.
PY - 1997/1/1
Y1 - 1997/1/1
N2 - Objective: To examine whether formal thought disorder and psychopathology occurred in children with complex partial seizures (CPS) rather than children with primary generalized epilepsy with absences (PGE) or nonepileptic children. Method: Formal thought disorder was coded in 30 children with CPS, 24 children with PGE, and 61 nonepileptic children, and structured interview-based psychiatric diagnoses were obtained for the epileptic subjects. Results: The CPS subjects had significantly more illogical thinking than the PGE and nonepileptic children. The severity of their illogical thinking was related to global cognitive dysfunction and a schizophrenia-like psychosis. Age of onset and seizure control, however, were significantly associated with the severity of illogical thinking in the PGE group. One or more psychiatric diagnoses were found in 63% of the CPS and 54% of the PGE patients, particularly if they had global cognitive deficits. Conclusion: Illogical thinking, associated with cognitive dysfunction or schizophrenia-like symptoms, might be a feature of pediatric CPS. Psychopathology might be related to global cognitive dysfunction in pediatric CPS and PGE.
AB - Objective: To examine whether formal thought disorder and psychopathology occurred in children with complex partial seizures (CPS) rather than children with primary generalized epilepsy with absences (PGE) or nonepileptic children. Method: Formal thought disorder was coded in 30 children with CPS, 24 children with PGE, and 61 nonepileptic children, and structured interview-based psychiatric diagnoses were obtained for the epileptic subjects. Results: The CPS subjects had significantly more illogical thinking than the PGE and nonepileptic children. The severity of their illogical thinking was related to global cognitive dysfunction and a schizophrenia-like psychosis. Age of onset and seizure control, however, were significantly associated with the severity of illogical thinking in the PGE group. One or more psychiatric diagnoses were found in 63% of the CPS and 54% of the PGE patients, particularly if they had global cognitive deficits. Conclusion: Illogical thinking, associated with cognitive dysfunction or schizophrenia-like symptoms, might be a feature of pediatric CPS. Psychopathology might be related to global cognitive dysfunction in pediatric CPS and PGE.
KW - Child
KW - Complex partial seizures
KW - Formal thought disorder
KW - Primary generalized epilepsy
KW - Psychopathology
UR - http://www.scopus.com/inward/record.url?scp=0030823383&partnerID=8YFLogxK
U2 - 10.1097/00004583-199709000-00022
DO - 10.1097/00004583-199709000-00022
M3 - Article
AN - SCOPUS:0030823383
SN - 0890-8567
VL - 36
SP - 1286
EP - 1294
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
IS - 9
ER -