Formation of Anhydrides by Homogeneous Palladium(II)-Catalyzed Carbonylation of Aryl Halides and Metal Carboxylates

Ilan Pri-Bar, Howard Alper

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Aryl iodides react with sodium, potassium, or calcium carboxylates and carbon monoxide in N,N-dimethyl-formamide, in the presence of palladium acetate, to give acid anhydrides. The reaction proceeds under mild conditions (50–90 °C, 2.7 atm), affording anhydrides in reasonable yields. The reaction is applicable to bromobenzene, provided one uses higher temperatures or adds tetrabutylammonium iodide. An acylpalladium carboxylate may be a key intermediate in these reactions.

Original languageEnglish
Pages (from-to)36-38
Number of pages3
JournalJournal of Organic Chemistry
Volume54
Issue number1
DOIs
StatePublished - 1 Jan 1989
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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