TY - JOUR
T1 - Four-component, three-step cascade reaction
T2 - an effective synthesis of indazole-fused triazolo[5,1-c]quinoxalines
AU - Shiva Kumar, K.
AU - Naikawadi, Praveen Kumar
AU - Rajesham, Bandari
AU - Rambabu, D.
N1 - Publisher Copyright:
© The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - An efficient four-component, three-step cascade reaction was developed for the synthesis of indazole-fused triazolo[5,1-c]quinoxalines from o-azido aldehyde, o-iodoaniline, phenylacetylene, and sodium azide. The methodology involves the sequential formation of 2H-indazole, then azide-alkyne cycloaddition, followed by C-N coupling, and finally intramolecular cross-dehydrogenative C-C coupling. Notable features of this protocol include simple starting materials, reduced synthetic steps, and good yields.
AB - An efficient four-component, three-step cascade reaction was developed for the synthesis of indazole-fused triazolo[5,1-c]quinoxalines from o-azido aldehyde, o-iodoaniline, phenylacetylene, and sodium azide. The methodology involves the sequential formation of 2H-indazole, then azide-alkyne cycloaddition, followed by C-N coupling, and finally intramolecular cross-dehydrogenative C-C coupling. Notable features of this protocol include simple starting materials, reduced synthetic steps, and good yields.
UR - http://www.scopus.com/inward/record.url?scp=85062854837&partnerID=8YFLogxK
U2 - 10.1039/C8NJ06299D
DO - 10.1039/C8NJ06299D
M3 - Article
AN - SCOPUS:85062854837
SN - 1144-0546
VL - 43
SP - 4333
EP - 4337
JO - New Journal of Chemistry
JF - New Journal of Chemistry
IS - 11
ER -