Abstract
In laser desorption of a series of cyclically 9-substituted adenines, followed by multiphoton ionization, we observed characteristic fragmentation. This is in marked contrast to laser desorption under identical conditions of cyclically 9-substituted guanines, for which we obtained predominantly the parent mass. By applying resonant 2 photon ionization spectroscopy (R2PI) to the laser-desorbed, jet-cooled fragments, we show that the fragmentation is induced by the desorption process and not by the excitation/ionization process. Fragmentation takes place between C′2 and C′3 and between C′1 and O6 in the sugar ring. By adding a propyl bridge between C′2 and C′3, the fragmentation pathway changes to a cleavage of the C′4-C′5 bond in the sugar ring. This allowed us to record R2PI spectra of a fragment species that can serve as a model for adenosine.
Original language | English |
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Pages (from-to) | 133-138 |
Number of pages | 6 |
Journal | International Journal of Mass Spectrometry |
Volume | 219 |
Issue number | 1 |
DOIs | |
State | Published - 1 Aug 2002 |
Externally published | Yes |
Keywords
- Adenines
- DNA bases
- Fragmentation
- Jet-cooling
- Laser desorption
- R2PI spectrum
ASJC Scopus subject areas
- Instrumentation
- Condensed Matter Physics
- Spectroscopy
- Physical and Theoretical Chemistry