Frequency demodulation with magnetoelectric coreshells: A novel approach to enhanced bio-stimulation

Ram Prasadh Narayanan, Ali Khaleghi, Ilangko Balasingham

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Magnetoelectric (ME) coreshell devices have interesting applications in biomedical technologies including biosensing, and communication, due to their strong inter - coupling between the magnetostrictive core and the piezoelectric shell. This property could be utilized for specific applications in localized bio - stimulation of cells. This paper provides a conceptual proof of using the non - linear property of ME coreshell devices for frequency demodulation and stimulation. We use the Multiphysics simulation approach, wherein the ME coreshell was biased with a DC magnetic field and perturbed through dual coil alternating magnetic fields. The combined effect of the ME non - linear magnetostriction and the dual coil perturbation resulted in the demodulation of the interference frequency component, that induced equivalent 'electrical hotspots' on the piezoelectric shell. We provide a cross model verification, where the generated electrical current density on the piezo shell was provided as an input to a Hodgkin - Huxley (HH) neural cell model to actively induce membrane potentials on the cell. Future applications as a standalone, battery- and electronics-free, controllable, multi - functional and localized coreshells for targeted drug delivery, backscatter communication and bio - stimulation, is envisioned.

Original languageEnglish
Title of host publicationNanoCom 2023 - Proceedings of the 10th ACM International Conference on Nanoscale Computing and Communication
PublisherAssociation for Computing Machinery, Inc
Pages59-64
Number of pages6
ISBN (Electronic)9798400700347
DOIs
StatePublished - 20 Sep 2023
Externally publishedYes
Event10th ACM International Conference on Nanoscale Computing and Communication, NANOCOM 2023 - Coventry, United Kingdom
Duration: 20 Sep 202322 Sep 2023

Publication series

NameNanoCom 2023 - Proceedings of the 10th ACM International Conference on Nanoscale Computing and Communication

Conference

Conference10th ACM International Conference on Nanoscale Computing and Communication, NANOCOM 2023
Country/TerritoryUnited Kingdom
CityCoventry
Period20/09/2322/09/23

Keywords

  • Cell stimulation
  • localized frequency demodulation
  • Magnetoelectric coreshells

ASJC Scopus subject areas

  • Computational Theory and Mathematics
  • Computer Networks and Communications
  • Communication

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