Frequency of positive family history in bipolar patients in a catchment-area population

Joyce Rachel Alexander; Jonathan Benjamin; Bernard Lerer; Miron Baron; Robert H. Belmaker

doi:10.1016/0278-5846(95)00018-Q

Frequency of positive family history in bipolar patients in a catchment-area population

Joyce Rachel Alexander, Jonathan Benjamin, Bernard Lerer, Miron Baron, Robert H. Belmaker

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

1. 1. Major family studies of bipolar disorder report the frequency of affective disorder among probands' relatives, but do not usually report the frequency of a positive family history among probands. A single previous study was not population based. 2. 2. The Division of Psychiatry of Ben Gurion University provides virtually all psychiatric services for a catchment area of 300,000 people. The authors reviewed the charts of all 236 treated bipolar I patients in 1991, and interviewed 177 of them with a modified FH-RDC. 3. 3. 48% of probands had a family history of mental illness. 4. 4. However, the present methods of ascertainment may have been insufficiently sensitive.

Original language	English
Pages (from-to)	367-373
Number of pages	7
Journal	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume	19
Issue number	3
DOIs	https://doi.org/10.1016/0278-5846(95)00018-Q
State	Published - 1 Jan 1995

Keywords

epidemiology
genetics
manic-depressive illness

ASJC Scopus subject areas

Pharmacology
Biological Psychiatry

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10.1016/0278-5846(95)00018-Q

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title = "Frequency of positive family history in bipolar patients in a catchment-area population",

abstract = "1. 1. Major family studies of bipolar disorder report the frequency of affective disorder among probands' relatives, but do not usually report the frequency of a positive family history among probands. A single previous study was not population based. 2. 2. The Division of Psychiatry of Ben Gurion University provides virtually all psychiatric services for a catchment area of 300,000 people. The authors reviewed the charts of all 236 treated bipolar I patients in 1991, and interviewed 177 of them with a modified FH-RDC. 3. 3. 48% of probands had a family history of mental illness. 4. 4. However, the present methods of ascertainment may have been insufficiently sensitive.",

keywords = "epidemiology, genetics, manic-depressive illness",

author = "Alexander, {Joyce Rachel} and Jonathan Benjamin and Bernard Lerer and Miron Baron and Belmaker, {Robert H.}",

note = "Funding Information: The authors thank Professor Benjamin Maoz, M.D., Ph.D., the Director of the Soroka Medical Centre Psychiatric Service, for his cooperation and support. The study was supported by NIMH Research Scientist Award MH00176 (Dr. Baron) and NIMH grant MH43979.",

year = "1995",

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doi = "10.1016/0278-5846(95)00018-Q",

language = "English",

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pages = "367--373",

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T1 - Frequency of positive family history in bipolar patients in a catchment-area population

AU - Alexander, Joyce Rachel

AU - Benjamin, Jonathan

AU - Lerer, Bernard

AU - Baron, Miron

AU - Belmaker, Robert H.

N1 - Funding Information: The authors thank Professor Benjamin Maoz, M.D., Ph.D., the Director of the Soroka Medical Centre Psychiatric Service, for his cooperation and support. The study was supported by NIMH Research Scientist Award MH00176 (Dr. Baron) and NIMH grant MH43979.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - 1. 1. Major family studies of bipolar disorder report the frequency of affective disorder among probands' relatives, but do not usually report the frequency of a positive family history among probands. A single previous study was not population based. 2. 2. The Division of Psychiatry of Ben Gurion University provides virtually all psychiatric services for a catchment area of 300,000 people. The authors reviewed the charts of all 236 treated bipolar I patients in 1991, and interviewed 177 of them with a modified FH-RDC. 3. 3. 48% of probands had a family history of mental illness. 4. 4. However, the present methods of ascertainment may have been insufficiently sensitive.

AB - 1. 1. Major family studies of bipolar disorder report the frequency of affective disorder among probands' relatives, but do not usually report the frequency of a positive family history among probands. A single previous study was not population based. 2. 2. The Division of Psychiatry of Ben Gurion University provides virtually all psychiatric services for a catchment area of 300,000 people. The authors reviewed the charts of all 236 treated bipolar I patients in 1991, and interviewed 177 of them with a modified FH-RDC. 3. 3. 48% of probands had a family history of mental illness. 4. 4. However, the present methods of ascertainment may have been insufficiently sensitive.

KW - epidemiology

KW - genetics

KW - manic-depressive illness

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U2 - 10.1016/0278-5846(95)00018-Q

DO - 10.1016/0278-5846(95)00018-Q

M3 - Article

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SN - 0278-5846

VL - 19

SP - 367

EP - 373

JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry

JF - Progress in Neuro-Psychopharmacology and Biological Psychiatry

IS - 3

ER -

Frequency of positive family history in bipolar patients in a catchment-area population

Abstract

Keywords

ASJC Scopus subject areas

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