Frequency regulation demonstrated by coupling a model and a biological neuron

Yair Manor; Farzan Nadim

doi:10.1016/S0925-2312(01)00394-0

Frequency regulation demonstrated by coupling a model and a biological neuron

Yair Manor, Farzan Nadim

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Using a 2-cell reciprocally inhibitory network consisting of a biological pacemaker neuron and a model neuron integrated in real time, we show that if both synapses are depressing there is a wide range of bistability in the system. The two stable outputs are both oscillatory, but one is controlled by the intrinsic properties of the biological pacemaker neuron, whereas the other is controlled by the strength of the depressing synapses.

Original language	English
Pages (from-to)	269-278
Number of pages	10
Journal	Neurocomputing
Volume	38-40
DOIs	https://doi.org/10.1016/S0925-2312(01)00394-0
State	Published - 1 Jun 2001

Keywords

Bursting
Oscillation
Pacemaker
Synaptic depression

ASJC Scopus subject areas

Computer Science Applications
Cognitive Neuroscience
Artificial Intelligence

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10.1016/S0925-2312(01)00394-0

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title = "Frequency regulation demonstrated by coupling a model and a biological neuron",

abstract = "Using a 2-cell reciprocally inhibitory network consisting of a biological pacemaker neuron and a model neuron integrated in real time, we show that if both synapses are depressing there is a wide range of bistability in the system. The two stable outputs are both oscillatory, but one is controlled by the intrinsic properties of the biological pacemaker neuron, whereas the other is controlled by the strength of the depressing synapses.",

keywords = "Bursting, Oscillation, Pacemaker, Synaptic depression",

author = "Yair Manor and Farzan Nadim",

note = "Funding Information: This work was supported by The Israel Science Foundation 314/99-1 (YM), the Zlotowski Center for Neuroscience (YM), the Alfred P. Sloan Foundation (FN) and the New Jersey Institute of Technology 421140 (FN). ",

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AU - Manor, Yair

AU - Nadim, Farzan

N1 - Funding Information: This work was supported by The Israel Science Foundation 314/99-1 (YM), the Zlotowski Center for Neuroscience (YM), the Alfred P. Sloan Foundation (FN) and the New Jersey Institute of Technology 421140 (FN).

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Y1 - 2001/6/1

N2 - Using a 2-cell reciprocally inhibitory network consisting of a biological pacemaker neuron and a model neuron integrated in real time, we show that if both synapses are depressing there is a wide range of bistability in the system. The two stable outputs are both oscillatory, but one is controlled by the intrinsic properties of the biological pacemaker neuron, whereas the other is controlled by the strength of the depressing synapses.

AB - Using a 2-cell reciprocally inhibitory network consisting of a biological pacemaker neuron and a model neuron integrated in real time, we show that if both synapses are depressing there is a wide range of bistability in the system. The two stable outputs are both oscillatory, but one is controlled by the intrinsic properties of the biological pacemaker neuron, whereas the other is controlled by the strength of the depressing synapses.

KW - Bursting

KW - Oscillation

KW - Pacemaker

KW - Synaptic depression

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SP - 269

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JO - Neurocomputing

JF - Neurocomputing

ER -

Frequency regulation demonstrated by coupling a model and a biological neuron

Abstract

Keywords

ASJC Scopus subject areas

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