Abstract
The role of prostaglandins (PGs) in phagocytosis of sheep erythrocytes (SRC) by mouse spleen adherent cells was examined. A decrease of about 50% in the phagocytosis was observed when macrophages were treated with 5 microgram/ml indomethacin. Concomitant addition of PGs (10(-6) mg/ml), however, prevented the inhibitory effect of indomethacin. It is thus suggested that PGs play an important role in phagocytosis.
Original language | English |
---|---|
Pages (from-to) | 413-417 |
Number of pages | 5 |
Journal | Advances in Experimental Medicine and Biology |
Volume | 121 |
Issue number | A |
State | Published - 1 Dec 1979 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology