Function of macrophage prostaglandins in the process of phagocytosis.

E. Razin, U. Zor, A. Globerson

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The role of prostaglandins (PGs) in phagocytosis of sheep erythrocytes (SRC) by mouse spleen adherent cells was examined. A decrease of about 50% in the phagocytosis was observed when macrophages were treated with 5 microgram/ml indomethacin. Concomitant addition of PGs (10(-6) mg/ml), however, prevented the inhibitory effect of indomethacin. It is thus suggested that PGs play an important role in phagocytosis.

Original languageEnglish
Pages (from-to)413-417
Number of pages5
JournalAdvances in Experimental Medicine and Biology
Issue numberA
StatePublished - 1 Dec 1979

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (all)


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