Functions of Local Circuits in Neocortex: Synchrony and Laminae

Barry W. Connors, Yael Amitai

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


This chapter focuses on one feature of the local cortical circuit that has been relatively neglected but which is particularly important and probably widespread. The neurons that provide output from the neocortex are largely found in layer V. This location alone makes it indispensable, but there are several other characteristics of structure and function that distinguish layer V. The basic hypothesis is that the neural network within layer V is uniquely capable of ordering, controlling, coordinating, and synchronizing the activity of the neocortex. The chapter outlines some reasons for proposing this hypothesis and speculates about its significance.

Original languageEnglish
Title of host publicationThe Cortical Neuron
PublisherOxford University Press
ISBN (Electronic)9780199847464
ISBN (Print)9780195083309
StatePublished - 22 Mar 2012


  • Cortical circuit
  • Layer v
  • Neocortex
  • Neurons

ASJC Scopus subject areas

  • General Neuroscience


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