Gamma aminobutyric acid (GABA) levels in the CSF were measured in 9 normal individuals, 17 drug-free schizophrenic patients and 10 of these same schizophrenic patients after neuroleptic treatment. There was no significant difference between CSF level of GABA in the control group compared to those in schizophrenic patients; however, 6 of the 7 lowest GABA levels were from schizophrenic patients. There was a significant decline of 12 percent in mean GABA levels in the CSF after a mean of two months of neuroleptic treatment.
|Number of pages||4|
|Journal||British Journal of Psychiatry|
|State||Published - 1 Jan 1978|
ASJC Scopus subject areas
- Psychiatry and Mental health