GeneCards™ 2002: Towards a complete, object-oriented, human gene compendium

Marilyn Safran; Irina Solomon; Orit Shmueli; Michal Lapidot; Shai Shen-Orr; Avital Adato; Uri Ben-Dor; Nir Esterman; Naomi Rosen; Inga Peter; Tsviya Olender; Vered Chalifa-Caspi; Doron Lancet

doi:10.1093/bioinformatics/18.11.1542

GeneCards™ 2002: Towards a complete, object-oriented, human gene compendium

Marilyn Safran, Irina Solomon, Orit Shmueli, Michal Lapidot, Shai Shen-Orr, Avital Adato, Uri Ben-Dor, Nir Esterman, Naomi Rosen, Inga Peter, Tsviya Olender, Vered Chalifa-Caspi, Doron Lancet

Research output: Contribution to journal › Article › peer-review

175 Scopus citations

Abstract

Motivation: In the post-genomic era, functional analysis of genes requires a sophisticated interdisciplinary arsenal. Comprehensive resources are challenged to provide consistently improving, state-of-the-art tools. Results: GeneCards (Rebhan et al., 1998) has made innovative strides: (a) regular updates and enhancements incorporating new genes enriched with sequences, genomic locations, cDNA assemblies, orthologies, medical information, 3D protein structures, gene expression, and focused SNP summaries; (b) restructured software using object-oriented Perl, migration to schema-driven XML, and (c) pilot studies, introducing methods to produce cards for novel and predicted genes.

Original language	English
Pages (from-to)	1542-1543
Number of pages	2
Journal	Bioinformatics
Volume	18
Issue number	11
DOIs	https://doi.org/10.1093/bioinformatics/18.11.1542
State	Published - 1 Nov 2002
Externally published	Yes

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

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10.1093/bioinformatics/18.11.1542

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title = "GeneCards{\texttrademark} 2002: Towards a complete, object-oriented, human gene compendium",

abstract = "Motivation: In the post-genomic era, functional analysis of genes requires a sophisticated interdisciplinary arsenal. Comprehensive resources are challenged to provide consistently improving, state-of-the-art tools. Results: GeneCards (Rebhan et al., 1998) has made innovative strides: (a) regular updates and enhancements incorporating new genes enriched with sequences, genomic locations, cDNA assemblies, orthologies, medical information, 3D protein structures, gene expression, and focused SNP summaries; (b) restructured software using object-oriented Perl, migration to schema-driven XML, and (c) pilot studies, introducing methods to produce cards for novel and predicted genes.",

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doi = "10.1093/bioinformatics/18.11.1542",

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T2 - Towards a complete, object-oriented, human gene compendium

AU - Safran, Marilyn

AU - Solomon, Irina

AU - Shmueli, Orit

AU - Lapidot, Michal

AU - Shen-Orr, Shai

AU - Adato, Avital

AU - Ben-Dor, Uri

AU - Esterman, Nir

AU - Rosen, Naomi

AU - Peter, Inga

AU - Olender, Tsviya

AU - Chalifa-Caspi, Vered

AU - Lancet, Doron

N1 - Funding Information: This work was supported by the Weizmann Institute Crown Human Genome Center and by DoubleTwist Inc.

PY - 2002/11/1

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GeneCards™ 2002: Towards a complete, object-oriented, human gene compendium

Abstract

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