GeneNote: Whole genome expression profiles in normal human tissues

Orit Shmueli, Shirley Horn-Saban, Vered Chalifa-Caspi, Michael Shmoish, Ron Ophir, Hila Benjamin-Rodrig, Marilyn Safran, Eytan Domany, Doron Lancet

Research output: Contribution to journalArticlepeer-review

140 Scopus citations

Abstract

A novel data set, GeneNote (Gene Normal Tissue Expression), was produced to portray complete gene expression profiles in healthy human tissues using the Affymetrix GeneChip HG-U95 set, which includes 62 839 probe-sets. The hybridization intensities of two replicates were processed and analyzed to yield the complete transcriptome for twelve human tissues. Abundant novel information on tissue specificity provides a baseline for past and future expression studies related to diseases. The data is posted in GeneNote (http://genecards.weizmann.ac.il/genenote/), a widely used compendium of human genes (http://bioinfo.weizmann.ac.il/genecard).

Original languageEnglish
Pages (from-to)1067-1072
Number of pages6
JournalComptes Rendus - Biologies
Volume326
Issue number10-11
DOIs
StatePublished - 1 Jan 2003
Externally publishedYes

Keywords

  • Expression profile
  • GeneCards
  • Microarray
  • Normal human tissues
  • Transcriptome

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