Genetic factors in neuromuscular pain

Dan Buskila, Lily Neumann, Joseph Press

    Research output: Contribution to journalReview articlepeer-review

    28 Scopus citations

    Abstract

    Recent evidence suggests that fibromyalgia, a chronic widespread pain condition and related syndromes (chronic fatigue syndrome, irritable bowel syndrome, etc.) may share heritable pathophysiologic features. We review the recent literature on genetic and familial factors found to participate in the pathogenesis of these syndromes, specifically fibromyalgia, including evidence suggesting that serotonin- and dopamine-related genes may play a role in the pathogenesis of these illnesses. The importance of environmental factors triggering these conditions in predisposed individuals is also discussed.

    Original languageEnglish
    Pages (from-to)281-284
    Number of pages4
    JournalCNS Spectrums
    Volume10
    Issue number4
    DOIs
    StatePublished - 1 Jan 2005

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