Glucose-6-phosphatase induction by triamcinolone in human liver

Shimon W. Moses; Stanley Levin; Reuben Chayoth; Kurt Steinitz

doi:10.1016/0024-3205(66)90139-1

Glucose-6-phosphatase induction by triamcinolone in human liver

Shimon W. Moses, Stanley Levin, Reuben Chayoth, Kurt Steinitz

Research output: Contribution to journal › Article › peer-review

Abstract

Glucose-6-phosphatase activity of the liver was found to be markedly subnormal in two cases of glycogen storage disease type III (amylo-1, 6-glucosidase deficiency). Induction of glucose-6-phosphatase activity could be obtained by triamcinolone administration. This suggests that the subnormal activity of this enzyme found in these cases was due to a regulatory disorder of enzyme biosynthesis and not due to a structural mutation.

Original language	English
Pages (from-to)	219-222
Number of pages	4
Journal	Life Sciences
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/0024-3205(66)90139-1
State	Published - 1 Jan 1966
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Pharmacology, Toxicology and Pharmaceutics

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10.1016/0024-3205(66)90139-1

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title = "Glucose-6-phosphatase induction by triamcinolone in human liver",

abstract = "Glucose-6-phosphatase activity of the liver was found to be markedly subnormal in two cases of glycogen storage disease type III (amylo-1, 6-glucosidase deficiency). Induction of glucose-6-phosphatase activity could be obtained by triamcinolone administration. This suggests that the subnormal activity of this enzyme found in these cases was due to a regulatory disorder of enzyme biosynthesis and not due to a structural mutation.",

author = "Moses, {Shimon W.} and Stanley Levin and Reuben Chayoth and Kurt Steinitz",

note = "Funding Information: Supported in part by a research great of the National Institutes of Health, AM-08302-O1 .",

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AU - Moses, Shimon W.

AU - Levin, Stanley

AU - Chayoth, Reuben

AU - Steinitz, Kurt

N1 - Funding Information: Supported in part by a research great of the National Institutes of Health, AM-08302-O1 .

PY - 1966/1/1

Y1 - 1966/1/1

N2 - Glucose-6-phosphatase activity of the liver was found to be markedly subnormal in two cases of glycogen storage disease type III (amylo-1, 6-glucosidase deficiency). Induction of glucose-6-phosphatase activity could be obtained by triamcinolone administration. This suggests that the subnormal activity of this enzyme found in these cases was due to a regulatory disorder of enzyme biosynthesis and not due to a structural mutation.

AB - Glucose-6-phosphatase activity of the liver was found to be markedly subnormal in two cases of glycogen storage disease type III (amylo-1, 6-glucosidase deficiency). Induction of glucose-6-phosphatase activity could be obtained by triamcinolone administration. This suggests that the subnormal activity of this enzyme found in these cases was due to a regulatory disorder of enzyme biosynthesis and not due to a structural mutation.

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U2 - 10.1016/0024-3205(66)90139-1

DO - 10.1016/0024-3205(66)90139-1

M3 - Article

AN - SCOPUS:49949132080

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SP - 219

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ER -

Glucose-6-phosphatase induction by triamcinolone in human liver

Abstract

ASJC Scopus subject areas

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