TY - JOUR
T1 - Glycemic Control and Diabetes Related Complications in Adults with Type 1 Diabetes Mellitus and ADHD
AU - Vinker-Shuster, Michal
AU - Eldor, Roy
AU - Green, Ilan
AU - Golan-Cohen, Avivit
AU - Manor, Iris
AU - Merzon, Eugene
N1 - Publisher Copyright:
© The Author(s) 2021.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Objective: To assess the correlation of co-morbid ADHD and diabetes-related complications in patients with type-1-diabetes-mellitus (T1DM). Methods: A retrospective cross-sectional study was conducted during 2018 using the Leumit-Health-Services(LHS) database. Diabetes-related complications were assessed in patients with T1DM and ADHD (T1DM-ADHD+) and compared with patients with T1DM alone (T1DM-ADHD−). Results: Out of 789 adult-patients with T1DM, 75 (9.5%) were T1DM-ADHD+, matched to 225 T1DM-ADHD−. HbA1C levels were higher in T1DM-ADHD+ patients (8.1% ± 1.6 vs. 7.4% ± 1.2, p <.01), as well as diabetes-related complications: neuropathy (22.7% vs. 5.8%, p <.01), ulcers (8% vs. 0.9%, p <.05), limb amputation (5.3% vs. 0.9%, p <.05), albuminuria (15.5% vs. 2.8%, p <.01), chronic renal failure (10.6% vs. 2.5%, p =.01), and emergency room admissions rate (26.7% vs. 15.1%, p <.05). In sub-analysis, lower average HbA1C levels and diabetic ulcer rates were found among ADHD patients treated with stimulants, all p <.05. Conclusion: Co-morbidity of ADHD and T1DM is associated with poor glycemic control and higher complication rates.
AB - Objective: To assess the correlation of co-morbid ADHD and diabetes-related complications in patients with type-1-diabetes-mellitus (T1DM). Methods: A retrospective cross-sectional study was conducted during 2018 using the Leumit-Health-Services(LHS) database. Diabetes-related complications were assessed in patients with T1DM and ADHD (T1DM-ADHD+) and compared with patients with T1DM alone (T1DM-ADHD−). Results: Out of 789 adult-patients with T1DM, 75 (9.5%) were T1DM-ADHD+, matched to 225 T1DM-ADHD−. HbA1C levels were higher in T1DM-ADHD+ patients (8.1% ± 1.6 vs. 7.4% ± 1.2, p <.01), as well as diabetes-related complications: neuropathy (22.7% vs. 5.8%, p <.01), ulcers (8% vs. 0.9%, p <.05), limb amputation (5.3% vs. 0.9%, p <.05), albuminuria (15.5% vs. 2.8%, p <.01), chronic renal failure (10.6% vs. 2.5%, p =.01), and emergency room admissions rate (26.7% vs. 15.1%, p <.05). In sub-analysis, lower average HbA1C levels and diabetic ulcer rates were found among ADHD patients treated with stimulants, all p <.05. Conclusion: Co-morbidity of ADHD and T1DM is associated with poor glycemic control and higher complication rates.
KW - ADHD
KW - HbAC
KW - diabetes
KW - type 1 diabetes
UR - http://www.scopus.com/inward/record.url?scp=85122100490&partnerID=8YFLogxK
U2 - 10.1177/10870547211068039
DO - 10.1177/10870547211068039
M3 - Article
C2 - 34933573
AN - SCOPUS:85122100490
SN - 1087-0547
VL - 26
SP - 1235
EP - 1244
JO - Journal of Attention Disorders
JF - Journal of Attention Disorders
IS - 9
ER -
