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Glycerol triacetate as solvent and acyl donor in the production of isoamyl acetate with Candida antarctica lipase B

  • Adi Wolfson
  • , Aviad Atyya
  • , Christina Dlugy
  • , Dorith Tavor

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

Glycerol triacetate was successfully used as a green solvent and as the acyl donor in the transesterification of isoamyl alcohol to produce isoamyl acetate using free and immobilized Candida antarctica lipase B. Immobilized lipase was more catalytically active than free lipase and could be easily separated from the reaction mixture by filtration. In addition, it was found that increasing either the reaction temperature or the enzyme to substrate ratio increased the conversion of isoamyl alcohol. Using triacetin as the solvent also enabled the separation of product by simple extraction with petroleum ether and catalyst recycling.

Original languageEnglish
Pages (from-to)363-366
Number of pages4
JournalBioprocess and Biosystems Engineering
Volume33
Issue number3
DOIs
StatePublished - 1 Mar 2010
Externally publishedYes

Keywords

  • Green solvent
  • Isoamyl acetate
  • Lipase
  • Triacetin

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

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