Haemophilus influenzae: A significant pathogen in acute otitis media

Eugene Leibovitz, Michael R. Jacobs, Ron Dagan

    Research output: Contribution to journalReview articlepeer-review

    161 Scopus citations

    Abstract

    Haemophilus influenzae is a major pathogen in acute otitis media (AOM) causing disease that is not clinically distinguishable from that caused by Streptococcus pneumoniae. AOM caused by H. influenzae is particularly associated with older age and recurrent disease. Antibiotics differ in their ability to eradicate H. influenzae from the middle ear space. In the United States, widespread pneumococcal vaccination has increased the importance of H. influenzae as a major theraputic challenge in the treatment of AOM.

    Original languageEnglish
    Pages (from-to)1142-1153
    Number of pages12
    JournalPediatric Infectious Disease Journal
    Volume23
    Issue number12
    DOIs
    StatePublished - 1 Dec 2004

    Keywords

    • Acute otitis
    • Antibiotic resistance
    • Antimicrobials
    • Haemophilus influenzae
    • Media

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Microbiology (medical)
    • Infectious Diseases

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