Haemophilus influenzae: A significant pathogen in acute otitis media

Eugene Leibovitz, Michael R. Jacobs, Ron Dagan

Research output: Contribution to journalReview articlepeer-review

150 Scopus citations


Haemophilus influenzae is a major pathogen in acute otitis media (AOM) causing disease that is not clinically distinguishable from that caused by Streptococcus pneumoniae. AOM caused by H. influenzae is particularly associated with older age and recurrent disease. Antibiotics differ in their ability to eradicate H. influenzae from the middle ear space. In the United States, widespread pneumococcal vaccination has increased the importance of H. influenzae as a major theraputic challenge in the treatment of AOM.

Original languageEnglish
Pages (from-to)1142-1153
Number of pages12
JournalPediatric Infectious Disease Journal
Issue number12
StatePublished - 1 Dec 2004
Externally publishedYes


  • Acute otitis
  • Antibiotic resistance
  • Antimicrobials
  • Haemophilus influenzae
  • Media


Dive into the research topics of 'Haemophilus influenzae: A significant pathogen in acute otitis media'. Together they form a unique fingerprint.

Cite this