Head and neck carcinoma in Fanconi's anaemia-report of a case and review of the literature

J. P. Lustig; G. Lugassy; A. Neder; E. Sigler

doi:10.1016/0964-1955(94)00044-5

Head and neck carcinoma in Fanconi's anaemia-report of a case and review of the literature

J. P. Lustig, G. Lugassy, A. Neder, E. Sigler

Barzilai University Medical Center

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

Fanconi's anaemia (FA) is a rare autosomal recessive syndrome characterised by progressive lethal pancytopenia, skeletal abnormalities, hyperpigmentation and increased chromosomal aberrations. A high incidence of leukaemia and hepatocellular and squamous cell carcinomas (SCC) have been reported in FA patients. A rare case of SCC of the dorsum of the tongue in a FA patient is presented. A review of the reported cases of head and neck carcinoma in FA patients shows a different male: female ratio than previously reported, and a high incidence of carcinoma of the tongue.

Original language	English
Pages (from-to)	68-72
Number of pages	5
Journal	European Journal of Cancer Part B: Oral Oncology
Volume	31
Issue number	1
DOIs	https://doi.org/10.1016/0964-1955(94)00044-5
State	Published - 1 Jan 1995

Keywords

Fanconi's anaemia
head and neck carcinoma

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0964-1955(94)00044-5

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AU - Lugassy, G.

AU - Neder, A.

AU - Sigler, E.

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AB - Fanconi's anaemia (FA) is a rare autosomal recessive syndrome characterised by progressive lethal pancytopenia, skeletal abnormalities, hyperpigmentation and increased chromosomal aberrations. A high incidence of leukaemia and hepatocellular and squamous cell carcinomas (SCC) have been reported in FA patients. A rare case of SCC of the dorsum of the tongue in a FA patient is presented. A review of the reported cases of head and neck carcinoma in FA patients shows a different male: female ratio than previously reported, and a high incidence of carcinoma of the tongue.

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Head and neck carcinoma in Fanconi's anaemia-report of a case and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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