TY - JOUR
T1 - Helicobacter pylori infection in rural settlements (kibbutzim) in Israel
AU - Gilboa, S.
AU - Gabay, G.
AU - Zamir, D.
AU - Zeev, A.
AU - Novis, B.
N1 - Funding Information:
ACKNOWLEDGEMENT The study was supported by grant from Ministry of Health, Chief Scientists's Office, Jerusalem.
PY - 1995/2/1
Y1 - 1995/2/1
N2 - Background. Helicobacter pylori (HP) is accepted as a major cause of type B gastritis, which is strongly associated with peptic ulcer disease. Epidemiological studies have indicated a correlation of HP infection and socioeconomic class.Methods. To determine the prevalence of HP infection and to evaluate symptoms and risk factors associated with HP infection in a rural population, 377 asymptomatic individuals were studied out of a random sample of 453 people. Subjects were randomly chosen in a ratio of 1:4 of all the adults over 30 years, living in eight communal settlements in Israel. Blood samples were taken and subjects answered a questionnaire in which sociodemographic information, clinical gastrointestinal background and the use of medication were included. A sensitive enzyme-linked immunoassay was used to determine antibodies to HP in serum.Results. The overall prevalence of HP infection was 72%. In a multivariant discriminant analysis: age, country of original and ethnic group were found to be the most closely associated variables for HP infection and the discriminant analysis succeeded in predicting correctly, in 62% of the population, whether they had or did not have HP infection. There was no significant difference with gender, occupation, educational level, blood group, smoking, gastrointestinal symptoms and use of medicationConclusions. The prevalence of HP infection was higher than that in Industrialized countries, but lower than in developing countries. The prevalence in a rural population was slightly higher than that of an urban population in Israel (65%). The country of origin and ethnic group influenced the prevalence of HP infection and not birth and growing up on the Kibbutz.
AB - Background. Helicobacter pylori (HP) is accepted as a major cause of type B gastritis, which is strongly associated with peptic ulcer disease. Epidemiological studies have indicated a correlation of HP infection and socioeconomic class.Methods. To determine the prevalence of HP infection and to evaluate symptoms and risk factors associated with HP infection in a rural population, 377 asymptomatic individuals were studied out of a random sample of 453 people. Subjects were randomly chosen in a ratio of 1:4 of all the adults over 30 years, living in eight communal settlements in Israel. Blood samples were taken and subjects answered a questionnaire in which sociodemographic information, clinical gastrointestinal background and the use of medication were included. A sensitive enzyme-linked immunoassay was used to determine antibodies to HP in serum.Results. The overall prevalence of HP infection was 72%. In a multivariant discriminant analysis: age, country of original and ethnic group were found to be the most closely associated variables for HP infection and the discriminant analysis succeeded in predicting correctly, in 62% of the population, whether they had or did not have HP infection. There was no significant difference with gender, occupation, educational level, blood group, smoking, gastrointestinal symptoms and use of medicationConclusions. The prevalence of HP infection was higher than that in Industrialized countries, but lower than in developing countries. The prevalence in a rural population was slightly higher than that of an urban population in Israel (65%). The country of origin and ethnic group influenced the prevalence of HP infection and not birth and growing up on the Kibbutz.
UR - http://www.scopus.com/inward/record.url?scp=0028920551&partnerID=8YFLogxK
U2 - 10.1093/ije/24.1.232
DO - 10.1093/ije/24.1.232
M3 - Article
C2 - 7797348
AN - SCOPUS:0028920551
SN - 0300-5771
VL - 24
SP - 232
EP - 237
JO - International Journal of Epidemiology
JF - International Journal of Epidemiology
IS - 1
ER -