Hepatitis C virus infection and genotypes in southern Israel and the Gaza Strip

Yonat Shemer-Avni, Zakaria El Astal, Oliver Kemper, Khamis Jawdat El Najjar, Arieh Yaari, Negba Hanuka, Miriam Margalith, Emanuel Sikuler

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The Gaza Strip borders the southern part of Israel and Egypt. There is a remarkable difference in the prevalence of antibodies to hepatitis C virus (HCV) between Israel (0.5%) and Egypt (10%). A few thousand inhabitants cross the borders daily from the Gaza Strip to both countries. The objectives of this study were to investigate the prevalence of HCV infection in the Gaza Strip, an area that was not studied before, and to study HCV transmission in the Gaza Strip by characterizing the genotypes of HCV in Southern Israel and the Gaza Strip and comparing them with those found in Egypt. HCV prevalence in the Gaza Strip was found to be 2.2%, relatively higher than in Israel but lower than in Egypt. The most common genotypes found were type lb in Southern israel and type 4 in the Gaza Strip, corresponding to the most prevalent genotype in Egypt. Similarity between type 4 isolates from the Gaza Strip and Egypt was illustrated further by sequence analysis of the HCV 5' noncoding region (NCR).

Original languageEnglish
Pages (from-to)230-233
Number of pages4
JournalJournal of Medical Virology
Volume56
Issue number3
DOIs
StatePublished - 1 Nov 1998

Keywords

  • Genotype
  • HCV
  • PCR
  • Prevalence

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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