Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives

Swati Halder, Uttpal Anand, Samapika Nandy, Patrik Oleksak, Safaa Qusti, Eida M. Alshammari, Gaber El-Saber Batiha, Eapen P. Koshy, Abhijit Dey

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Memory, one of the most vital aspects of the human brain, is necessary for the effective survival of an individual. ‘Memory’ can be defined in various ways but in an overall view, memory is the retention of the information that the brain grasps. Different factors are responsible for the disbalance in the brain's hippocampus region and the acetylcholine level, which masters the memory and cognitive functions. Plants are a source of pharmacologically potent drug molecules of high efficacy. Recently herbal medicine has evolved rapidly, gaining great acceptance worldwide due to their natural origin and fewer side effects. In this review, the authors have discussed the mechanisms and pharmacological action of herbal bioactive compounds to boost memory. Moreover, this review presents an update of different herbs and natural products that could act as memory enhancers and how they can be potentially utilized in the near future for the treatment of severe brain disorders. In addition, the authors also discuss the differences in biological activity of the same herb and emphasize the requirement for a higher standardization in cultivation methods and plant processing. The demand for further studies evaluating the interactions of herbal drugs is mentioned.

Original languageEnglish
Pages (from-to)879-907
Number of pages29
JournalSaudi Pharmaceutical Journal
Volume29
Issue number8
DOIs
StatePublished - 1 Aug 2021
Externally publishedYes

Keywords

  • Cognition
  • Herbal medicines
  • Memory enhancers
  • Memory impairment
  • Nootropics
  • Phytochemicals

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