Herpes zoster–typical and atypical presentations

Roy Rafael Dayan, Roni Peleg

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations

Abstract

Varicella- zoster virus infection is an intriguing medical entity that involves many medical specialties including infectious diseases, immunology, dermatology, and neurology. It can affect patients from early childhood to old age. Its treatment requires expertise in pain management and psychological support. While varicella is caused by acute viremia, herpes zoster occurs after the dormant viral infection, involving the cranial nerve or sensory root ganglia, is re-activated and spreads orthodromically from the ganglion, via the sensory nerve root, to the innervated target tissue (skin, cornea, auditory canal, etc.). Typically, a single dermatome is involved, although two or three adjacent dermatomes may be affected. The lesions usually do not cross the midline. Herpes zoster can also present with unique or atypical clinical manifestations, such as glioma, zoster sine herpete and bilateral herpes zoster, which can be a challenging diagnosis even for experienced physicians. We discuss the epidemiology, pathophysiology, diagnosis and management of Herpes Zoster, typical and atypical presentations.

Original languageEnglish
Pages (from-to)567-571
Number of pages5
JournalPostgraduate Medicine
Volume129
Issue number6
DOIs
StatePublished - 18 Aug 2017

Keywords

  • Herpes Zoster
  • anti-viral agents
  • bilateral herpes zoster
  • vaccinations for Herpes Zoster
  • zoster sine herpete

Fingerprint

Dive into the research topics of 'Herpes zoster–typical and atypical presentations'. Together they form a unique fingerprint.

Cite this