High-dose fentanyl patch for cancer pain

Sasson Menahem, Pesach Shvartzman

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations


    Objective: To describe a successful experience with a high dose (1000 μg/hr) of transdermal fentanyl for cancer pain relief. Case Report: A 62-year-old man suffering from rectal carcinoma was treated by our home care hospice unit during his last 3.5 months of life. At admission to our home care unit, he suffered mostly from severe anal pain (verbal pain scale of 10/10) due to advanced disease. He was then on 150 μg/hr transdermal fentanyl. Adjuvant therapy with amitriptyline 50 mg/day and dexamethasone 4 mg/day was added, but it did not relieve his pain. The dose of transdermal fentanyl was increased gradually to 1000 μg/hr with good pain control (verbal pain scale of 1 to 4/10 most of the time). Before his death, he was mentally alert with good pain control. Conclusions: High doses of transdermal fentanyl (1000 μg/hr; 10 patches) should be considered for pain relief in cancer patients.

    Original languageEnglish
    Pages (from-to)388-390
    Number of pages3
    JournalJournal of the American Board of Family Medicine
    Issue number5
    StatePublished - 1 Jan 2004

    ASJC Scopus subject areas

    • Public Health, Environmental and Occupational Health


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