High specific activity labelling of some tricyclic antidepressants

O. Buchman, I. Pri‐Bar

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Activated palladium is used as catalyst for the hydrogen‐tritium exchange in tricyclic antidepressants. The specific activities obtained are: desipramine: 44.9 Ci/mmol; imipramine: 14.9 Ci/mmol; notriptyline: 2.0 Ci/mmol and amitriptyline: 1.7 Ci/mmol.

Original languageEnglish
Pages (from-to)263-269
Number of pages7
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number2
StatePublished - 1 Jan 1978
Externally publishedYes


  • Amitriptyline
  • Desipramine
  • Imipramine
  • Nortriptyline
  • Tritiation

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry


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