Abstract
Activated palladium is used as catalyst for the hydrogen‐tritium exchange in tricyclic antidepressants. The specific activities obtained are: desipramine: 44.9 Ci/mmol; imipramine: 14.9 Ci/mmol; notriptyline: 2.0 Ci/mmol and amitriptyline: 1.7 Ci/mmol.
Original language | English |
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Pages (from-to) | 263-269 |
Number of pages | 7 |
Journal | Journal of Labelled Compounds and Radiopharmaceuticals |
Volume | 14 |
Issue number | 2 |
DOIs | |
State | Published - 1 Jan 1978 |
Externally published | Yes |
Keywords
- Amitriptyline
- Desipramine
- Imipramine
- Nortriptyline
- Tritiation
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Radiology Nuclear Medicine and imaging
- Drug Discovery
- Spectroscopy
- Organic Chemistry