Higher fasting plasma glucose levels, within the normal range, are associated with decreased processing speed in high functioning young elderly

Meytal Raizes, Odelia Elkana, Motty Franko, Ramit Ravona Springer, Shlomo Segev, Michal Schnaider Beeri

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

We explored the association of plasma glucose levels within the normal range with processing speed in high functioning young elderly, free of type 2 diabetes mellitus (T2DM). A sample of 41 participants (mean age = 64.7, SD = 10; glucose 94.5 mg/dL, SD = 9.3), were examined with a computerized cognitive battery. Hierarchical linear regression analysis showed that higher plasma glucose levels, albeit within the normal range (<110 mg/dL), were associated with longer reaction times (p < 0.01). These findings suggest that even in the subclinical range and in the absence of T2DM, monitoring plasma glucose levels may have an impact on cognitive function.

Original languageEnglish
Pages (from-to)589-592
Number of pages4
JournalJournal of Alzheimer's Disease
Volume49
Issue number3
DOIs
StatePublished - 1 Jan 2016
Externally publishedYes

Keywords

  • Cognitive function
  • Plasma glucose level
  • Processing speed
  • Type 2 diabetes

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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