Higher rates of tachysystole among patients with clinically apparent uterine leiomyomas

Eyal Sheiner, Tamar Biderman-Madar, Miriam Katz, Amalia Levy, Amnon Hadar, Moshe Mazor

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


This study was undertaken to determine uterine and fetal heart rate (FHR) tracing patterns associated with clinically apparent uterine leiomyomas. Uterine and FHR patterns of 44 women with diagnosed uterine leiomyomas were compared with 601 tracings of controls. Tracings were interpreted during the first stage of labor, using the National Institute of Child Health and Human Development Research Planning Workshop guidelines. Stratified analysis that used the Mantel-Haenszel technique was performed to control for confounders. Patients with leiomyomas had higher rates of uterine tachysystole as compared with those without leiomyomas (22.7% vs 1.3%; odds ratio [OR] = 21.8, 95% CI 7.4-65.6; P <. 001). No significant differences were noted between the groups regarding FHR patterns. Higher rates'of prostaglandin induction and oxytocin augmentation were noted in the uterine leiomyomas group (6.8% vs 0.8%; P =. 005 and 52.3% vs 10.5%; P <. 001, respectively). However, controlling for prostaglandin induction and oxytocin augmentation, with the use of the Mantel-Haenszel procedure, did not change the significant association between uterine leiomyomas and tachysystole (weighted OR 12.5, 95% CI 6.2-75.1, and weighted OR 8.7, 95% CI 3.6-43.1, respectively). Clinically apparent uterine leiomyomas, although not coupled with abnormal FHR patterns, are associated with higher rates of tachysystole.

Original languageEnglish
Pages (from-to)945-948
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Issue number3
StatePublished - 1 Sep 2004
Externally publishedYes


  • Fetal heart rate
  • Leiomyomas
  • Tachysystole

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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