Abstract
The history of the discovery and introduction of clozapine in clinical practice is very unusual and complex in comparison to other antipsychotics. In this chapter we review the complicated path from discovery through abrupt discontinuation of use and successful comeback as a unique treatment for patients with treatment resistant schizophrenia.
| Original language | English |
|---|---|
| Title of host publication | Clozapine |
| Subtitle of host publication | Medical Uses, Interactions and Side Effects |
| Publisher | Nova Science Publishers, Inc. |
| Pages | 1-13 |
| Number of pages | 13 |
| ISBN (Electronic) | 9781536169928 |
| State | Published - 1 Jan 2020 |
Keywords
- Antipsychotics
- Clozapine
- Plasticity
- Schizophrenia
- Treatment
ASJC Scopus subject areas
- General Medicine
- General Pharmacology, Toxicology and Pharmaceutics