Hodgkin lymphoma and hypothermia: Case report and review of the literature

Daniel Shepshelovich, Ofer Shpilberg, Meir Lahav, Gilad Itchaki, Maxim Yakimov, Pia Raanani, Amos Cohen

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

We report the development of hypothermia in a patient with Hodgkin lymphoma which resolved with chemotherapy administration. A review of the literature revealed 16 previous reports of hypothermia in patients with Hodgkin lymphoma. Overall prognosis seems to be unfavorable. To the best of our knowledge this is the first report of hypothermia in a patient with Hodgkin lymphoma transforming from chronic lymphocytic leukemia (Richter's syndrome). A possible pathophysiology could be paraneoplastic autonomic neuropathy. Physicians should be aware that Hodgkin lymphoma can present with hypothermia and should carefully monitor newly diagnosed patients with advanced disease for this complication. Likewise, patients with Hodgkin lymphoma who develop hypothermia should be screened for signs of autonomic neuropathy.

Original languageEnglish
Pages (from-to)227-230
Number of pages4
JournalActa Haematologica
Volume131
Issue number4
DOIs
StatePublished - 1 Jan 2014
Externally publishedYes

Keywords

  • Autonomic neuropathy
  • Hodgkin lymphoma
  • Hypothermia

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