How long do your angiographically normal coronary arteries remain normal? a pilot study

Jean Marc Weinstein; Carlos Cafri; Sergio Kobal; Michael Sherf; Reuben Ilia

doi:10.1177/0003319714531646

How long do your angiographically normal coronary arteries remain normal? a pilot study

Jean Marc Weinstein, Carlos Cafri, Sergio Kobal, Michael Sherf, Reuben Ilia

Research output: Contribution to journal › Article › peer-review

Abstract

Coronary atherosclerosis is a progressive disease. We sought to determine whether this fact also applies to patients at an advanced age with normal coronary arteries (NCAs) undergoing repeat catheterization at least 5 years later. Of the 189 patients who were found to have NCAs, 154 (81%) remained with NCAs and 35 (19%) developed obstructive coronary artery disease (OCAD). Development of OCAD was observed at all ages. Isolated risk factors were not associated with the appearance of OCAD, but the combination of diabetes mellitus with age >65 years or with smoking was associated with the appearance of OCAD (P =.04 for both). In conclusion, the finding of angiographically NCAs in elderly individuals does not prevent the later development of OCAD.

Original language	English
Pages (from-to)	262-264
Number of pages	3
Journal	Angiology
Volume	66
Issue number	3
DOIs	https://doi.org/10.1177/0003319714531646
State	Published - 1 Mar 2015

Keywords

Atherosclerosis
Normal coronary arteries
Progression
Risk factors

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/0003319714531646

Cite this

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abstract = "Coronary atherosclerosis is a progressive disease. We sought to determine whether this fact also applies to patients at an advanced age with normal coronary arteries (NCAs) undergoing repeat catheterization at least 5 years later. Of the 189 patients who were found to have NCAs, 154 (81%) remained with NCAs and 35 (19%) developed obstructive coronary artery disease (OCAD). Development of OCAD was observed at all ages. Isolated risk factors were not associated with the appearance of OCAD, but the combination of diabetes mellitus with age >65 years or with smoking was associated with the appearance of OCAD (P =.04 for both). In conclusion, the finding of angiographically NCAs in elderly individuals does not prevent the later development of OCAD.",

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T1 - How long do your angiographically normal coronary arteries remain normal? a pilot study

AU - Weinstein, Jean Marc

AU - Cafri, Carlos

AU - Kobal, Sergio

AU - Sherf, Michael

AU - Ilia, Reuben

N1 - Publisher Copyright: © The Author(s) 2014.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Coronary atherosclerosis is a progressive disease. We sought to determine whether this fact also applies to patients at an advanced age with normal coronary arteries (NCAs) undergoing repeat catheterization at least 5 years later. Of the 189 patients who were found to have NCAs, 154 (81%) remained with NCAs and 35 (19%) developed obstructive coronary artery disease (OCAD). Development of OCAD was observed at all ages. Isolated risk factors were not associated with the appearance of OCAD, but the combination of diabetes mellitus with age >65 years or with smoking was associated with the appearance of OCAD (P =.04 for both). In conclusion, the finding of angiographically NCAs in elderly individuals does not prevent the later development of OCAD.

AB - Coronary atherosclerosis is a progressive disease. We sought to determine whether this fact also applies to patients at an advanced age with normal coronary arteries (NCAs) undergoing repeat catheterization at least 5 years later. Of the 189 patients who were found to have NCAs, 154 (81%) remained with NCAs and 35 (19%) developed obstructive coronary artery disease (OCAD). Development of OCAD was observed at all ages. Isolated risk factors were not associated with the appearance of OCAD, but the combination of diabetes mellitus with age >65 years or with smoking was associated with the appearance of OCAD (P =.04 for both). In conclusion, the finding of angiographically NCAs in elderly individuals does not prevent the later development of OCAD.

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KW - Progression

KW - Risk factors

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How long do your angiographically normal coronary arteries remain normal? a pilot study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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