How to predict and diagnose postthrombotic syndrome

Anat Rabinovich, Susan R. Kahn

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Postthrombotic syndrome (PTS) is the most frequent complication of deep vein thrombosis (DVT). From 20% to 50% of the patients will develop PTS after DVT, and from 5% to 10%, severe PTS. PTS is diagnosed on clinical grounds, based on the presence of signs and symptoms of venous insufficiency in the leg ipsilateral to DVT. The Villalta scale, a clinical scale that incorporates venous symptoms and signs, is a recommended standard for the diagnosis of PTS. Identifying which patients are at high risk of developing PTS would help improve the management of patients with DVT and allow physicians to provide patients with individualized information on their expected prognosis. Clinical predictors of PTS have been progressively characterized, but the ability to predict which patient with DVT is likely to develop PTS remains limited. A number of risk factors for PTS have been identified; of these, proximal location of DVT and a previous ipsilateral DVT are the most important. This review discusses the knowledge gained over the last decade on the diagnosis and predictors of PTS. Copyright by Medycyna Praktyczna, 2014.

Original languageEnglish
Pages (from-to)410-416
Number of pages7
JournalPolish Archives of Internal Medicine
Issue number7-8
StatePublished - 1 Jan 2014
Externally publishedYes


  • Deep vein thrombosis
  • Diagnosis
  • Postthrombotic syndrome
  • Risk factors

ASJC Scopus subject areas

  • Internal Medicine


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