TY - JOUR
T1 - Human Cloning
T2 - Biology, Ethics, and Social Implications
AU - Bonetti, G.
AU - Donato, K.
AU - Medori, M. C.
AU - Dhuli, K.
AU - Henehan, G.
AU - Brown, R.
AU - Sieving, P.
AU - Sykora, P.
AU - Marks, R.
AU - Falsini, B.
AU - Capodicasa, N.
AU - Miertus, S.
AU - Lorusso, L.
AU - Dondossola, D.
AU - Tartaglia, G. M.
AU - Cerkez Ergoren, M.
AU - Dundar, M.
AU - Michelini, S.
AU - Malacarne, D.
AU - Beccari, T.
AU - Connelly, S. T.
AU - Martin, D.
AU - Bacu, A.
AU - Herbst, K. L.
AU - Kapustin, M.
AU - Stuppia, L.
AU - Lumer, L.
AU - Farronato, G.
AU - Bertelli, M.
PY - 2023/11/1
Y1 - 2023/11/1
N2 - Abstract: This scholarly article delves into the multifaceted domains of human cloning, encompassing its biological underpinnings, ethical dimensions, and broader societal implications. The exposition commences with a succinct historical and contextual overview of human cloning, segueing into an in-depth exploration of its biological intri-cacies. Central to this biological scrutiny is a comprehensive analysis of somatic cell nuclear transfer (SCNT) and its assorted iterations. The accomplishments and discoveries in cloning technology, such as successful animal cloning operations and advances in the efficiency and viability of cloned embryos, are reviewed. Future improvements, such as reprogramming procedures and gene editing technology, are also discussed. The discourse extends to ethical quandaries intrinsic to human cloning, entailing an extensive contemplation of values such as human dignity, autonomy, and safety. Furthermore, the ramifications of human cloning on a societal plane are subjected to scrutiny, with a dedicated emphasis on ramifications encompassing personal identity, kinship connections, and the fundamental notion of maternity. Culminating the analysis is a reiteration of the imperative to develop and govern human cloning technology judiciously and conscientiously. Finally, it discusses several ethical and practical issues, such as safety concerns, the possibility of exploitation, and the erosion of human dignity, and emphasizes the significance of carefully considering these issues.
AB - Abstract: This scholarly article delves into the multifaceted domains of human cloning, encompassing its biological underpinnings, ethical dimensions, and broader societal implications. The exposition commences with a succinct historical and contextual overview of human cloning, segueing into an in-depth exploration of its biological intri-cacies. Central to this biological scrutiny is a comprehensive analysis of somatic cell nuclear transfer (SCNT) and its assorted iterations. The accomplishments and discoveries in cloning technology, such as successful animal cloning operations and advances in the efficiency and viability of cloned embryos, are reviewed. Future improvements, such as reprogramming procedures and gene editing technology, are also discussed. The discourse extends to ethical quandaries intrinsic to human cloning, entailing an extensive contemplation of values such as human dignity, autonomy, and safety. Furthermore, the ramifications of human cloning on a societal plane are subjected to scrutiny, with a dedicated emphasis on ramifications encompassing personal identity, kinship connections, and the fundamental notion of maternity. Culminating the analysis is a reiteration of the imperative to develop and govern human cloning technology judiciously and conscientiously. Finally, it discusses several ethical and practical issues, such as safety concerns, the possibility of exploitation, and the erosion of human dignity, and emphasizes the significance of carefully considering these issues.
KW - Human cloning
KW - biology
KW - dignity
KW - ethical considerations
KW - safety
KW - social implications
UR - http://www.scopus.com/inward/record.url?scp=85177886609&partnerID=8YFLogxK
U2 - 10.7417/CT.2023.2492
DO - 10.7417/CT.2023.2492
M3 - Review article
C2 - 37994769
AN - SCOPUS:85177886609
SN - 0009-9074
VL - 174
SP - 230
EP - 235
JO - La Clinica terapeutica
JF - La Clinica terapeutica
IS - 6
ER -