Hybrid chitosan-based nanoparticulate systems for drug delivery

Kenguva Gowtham; Ananya Kar; Smruti Rekha Rout; Afsana Sheikh; Sushama Talegaonkar; Prashant Kesharwani; Rambabu Dandela

doi:10.1016/B978-0-323-85754-3.00007-1

Hybrid chitosan-based nanoparticulate systems for drug delivery

Kenguva Gowtham, Ananya Kar, Smruti Rekha Rout, Afsana Sheikh, Sushama Talegaonkar, Prashant Kesharwani, Rambabu Dandela

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

This chapter mainly focuses on drug delivery by utilizing hybrid chitosan (CS)-based drug delivery systems. CS is a cationic polysaccharide that is most importantly a chitin derivative and is a biodegradable natural polymer. But CS has not widely been used clinically due to its low solubility and mechanical properties. Hybrid CS possesses advanced biomedical application comparable to CS due to higher solubility and bioavailability. CS-inorganic materials were of particular concern due to the possible research and technological uses that have combined organic and inorganic species characteristics. This chapter describes the strategies to design different types of hybrid CS, different pathways of administration of hybrid CS, and various applications of hybrid CS.

Original language	English
Title of host publication	Hybrid Nanomaterials for Drug Delivery
Publisher	Elsevier
Pages	129-164
Number of pages	36
ISBN (Electronic)	9780323857543
ISBN (Print)	9780323903561
DOIs	https://doi.org/10.1016/B978-0-323-85754-3.00007-1
State	Published - 2 Jul 2022
Externally published	Yes

Keywords

Antibiotic properties
Chemotherapeutic agents
Drug delivery
Hybrid chitosan
Nanoparticles
Therapeutic

ASJC Scopus subject areas

General Medicine
General Biochemistry, Genetics and Molecular Biology

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10.1016/B978-0-323-85754-3.00007-1

Cite this

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abstract = "This chapter mainly focuses on drug delivery by utilizing hybrid chitosan (CS)-based drug delivery systems. CS is a cationic polysaccharide that is most importantly a chitin derivative and is a biodegradable natural polymer. But CS has not widely been used clinically due to its low solubility and mechanical properties. Hybrid CS possesses advanced biomedical application comparable to CS due to higher solubility and bioavailability. CS-inorganic materials were of particular concern due to the possible research and technological uses that have combined organic and inorganic species characteristics. This chapter describes the strategies to design different types of hybrid CS, different pathways of administration of hybrid CS, and various applications of hybrid CS.",

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AU - Kar, Ananya

AU - Rout, Smruti Rekha

AU - Sheikh, Afsana

AU - Talegaonkar, Sushama

AU - Kesharwani, Prashant

AU - Dandela, Rambabu

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KW - Chemotherapeutic agents

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KW - Nanoparticles

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Hybrid chitosan-based nanoparticulate systems for drug delivery

Abstract

Keywords

ASJC Scopus subject areas

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