Hybrid C₃N₄/Fluorine-Doped Tin Oxide Electrode Transfers Hydride for 1,4-NADH Cofactor Regeneration

Herein, we report the use of graphitic carbon nitride (C₃N₄)-modified fluorine-doped tin oxide electrodes for the electroregeneration of reduced nicotinamide adenine dinucleotide phosphate (NADH). We synthesized and functionalized these hybrid electrodes by using anodic aluminum-oxide-templated C₃N₄ growth. Electrochemical activation of the semiconducting C₃N₄ islands with a rhodium complex permits selective regeneration of biologically active 1,4-NADH cofactor. A ride for the hydride: Graphitic carbon nitride (C₃N₄)-modified fluorine-doped tin oxide (FTO) electrodes are used for the electroregeneration of reduced nicotinamide adenine dinucleotide phosphate (NADH). These hybrid electrodes are synthesized by using anodic aluminum-oxide-templated C₃N₄ growth. Electrochemical activation of the semiconducting C₃N₄ islands with a rhodium complex permits selective regeneration of biologically active 1,4-NADH cofactor.