Hydrogels from biopolymer hybrid for biomedical, food, and functional food applications

Lin Shu Liu, Joseph Kost, Fang Yan, Robert C. Spiro

Research output: Contribution to journalReview articlepeer-review

79 Scopus citations


Hybrid hydrogels from biopolymers have been applied for various indications across a wide range of biomedical, pharmaceutical, and functional food industries. In particular, hybrid hydrogels synthesized from two biopolymers have attracted increasing attention. The inclusion of a second biopolymer strengthens the stability of resultant hydrogels and enriches its functionalities by bringing in new functional groups or optimizing the micro-environmental conditions for certain biological and biochemical processes. This article presents approaches that have been used by our groups to synthesize biopolymer hybrid hydrogels for effective uses for immunotherapy, tissue regeneration, food and functional food applications. The research has achieved some challenging results, such as stabilizing physical structure, increasing mucoadhesiveness, and the creation of an artificial extracellular matrix to aid in guiding tissue differentiation.

Original languageEnglish
Pages (from-to)997-1011
Number of pages15
Issue number2
StatePublished - 25 Jun 2012


  • Biopolymer
  • Controlled drug delivery
  • Functional food
  • Hybrid
  • Hydrogel
  • Tissue engineering

ASJC Scopus subject areas

  • General Chemistry
  • Polymers and Plastics


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