Hydroxyethylstarch versus human albumin for the treatment of severe ovarian hyperstimulation syndrome: A preliminary report

Yoram Abramov, Muhammad Fatum, Dan Abrahamov, Joseph G. Schenker

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Objective: To compare the efficacy and safety of 6% hydroxyethylstarch and human albumin as colloid solutions for treatment of severe ovarian hyperstimulation syndrome (OHSS). Design: Controlled cohort study. Setting: Tertiary medical center. Patient(s): Sixteen patients with severe OHSS. Intervention(s): Six percent hydroxyethylstarch (6 patients) and human albumin (10 patients). Main Outcome Measure(s): Urine output, number of abdominal and pleural drainage procedures, complications, duration of hospitalization, and perinatal outcome. Result(s): Patients who received 6% hydroxyethylstarch had higher urine output, needed fewer abdominal and pleural paracenteses, and had a shorter hospital stay than those who received human albumin. In each group, no adverse effects or congenital malformations were observed and the rates of miscarriage were similar. Conclusion(s): These results suggest that 6% hydroxyethylstarch may be superior to albumin as a colloid solution for the treatment of severe OHSS.

Original languageEnglish
Pages (from-to)1228-1230
Number of pages3
JournalFertility and Sterility
Volume75
Issue number6
DOIs
StatePublished - 21 Jun 2001
Externally publishedYes

Keywords

  • Albumin
  • Colloid
  • Hydroxyethylstarch
  • Ovarian hyperstimulation syndrome
  • Treatment

Fingerprint

Dive into the research topics of 'Hydroxyethylstarch versus human albumin for the treatment of severe ovarian hyperstimulation syndrome: A preliminary report'. Together they form a unique fingerprint.

Cite this