Hyperreactive malarial splenomegaly and AIDs: Proguanil prevents recurrent pneumonia

Mark N. Lowenthal; Jacob Horowitz; Nava Gaspar; Mohammed Jabarren; Motti Klein; Martin I. Sacks; Tikva Yermihayu

doi:10.1016/S0035-9203(96)90267-9

Hyperreactive malarial splenomegaly and AIDs: Proguanil prevents recurrent pneumonia

Mark N. Lowenthal, Jacob Horowitz, Nava Gaspar, Mohammed Jabarren, Motti Klein, Martin I. Sacks, Tikva Yermihayu

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

An Ethiopian immigrated to Israel and gave a positive test result for human immunodeficiency virus. Soon after, he was thrice admitted to hospital in 3 months for severe pneumonia. Acquired immunodeficiency syndrome was diagnosed, as was hyperreactive malarial splenomegaly (HMS). Thereafter, during maintained proguanil treatment for HMS, the patient remained well for 16 months. Then, after another pneumonic illness, pneumococcal vaccine was administered. Proguanil was maintained for another 10 months and, despite declining CD4 cell counts, good health continued for a further 18 months.

Original language	English
Pages (from-to)	313-314
Number of pages	2
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	90
Issue number	3
DOIs	https://doi.org/10.1016/S0035-9203(96)90267-9
State	Published - 1 Jan 1996

Keywords

AIDS
Hyperreactive malarial splenomegaly
Pneumococcal vaccine
Pneumonia
Proguanil

ASJC Scopus subject areas

Parasitology
Public Health, Environmental and Occupational Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0035-9203(96)90267-9

Cite this

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title = "Hyperreactive malarial splenomegaly and AIDs: Proguanil prevents recurrent pneumonia",

abstract = "An Ethiopian immigrated to Israel and gave a positive test result for human immunodeficiency virus. Soon after, he was thrice admitted to hospital in 3 months for severe pneumonia. Acquired immunodeficiency syndrome was diagnosed, as was hyperreactive malarial splenomegaly (HMS). Thereafter, during maintained proguanil treatment for HMS, the patient remained well for 16 months. Then, after another pneumonic illness, pneumococcal vaccine was administered. Proguanil was maintained for another 10 months and, despite declining CD4 cell counts, good health continued for a further 18 months.",

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AU - Lowenthal, Mark N.

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AU - Gaspar, Nava

AU - Jabarren, Mohammed

AU - Klein, Motti

AU - Sacks, Martin I.

AU - Yermihayu, Tikva

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AB - An Ethiopian immigrated to Israel and gave a positive test result for human immunodeficiency virus. Soon after, he was thrice admitted to hospital in 3 months for severe pneumonia. Acquired immunodeficiency syndrome was diagnosed, as was hyperreactive malarial splenomegaly (HMS). Thereafter, during maintained proguanil treatment for HMS, the patient remained well for 16 months. Then, after another pneumonic illness, pneumococcal vaccine was administered. Proguanil was maintained for another 10 months and, despite declining CD4 cell counts, good health continued for a further 18 months.

KW - AIDS

KW - Hyperreactive malarial splenomegaly

KW - Pneumococcal vaccine

KW - Pneumonia

KW - Proguanil

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Hyperreactive malarial splenomegaly and AIDs: Proguanil prevents recurrent pneumonia

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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