Hypertrophy in labial capillary malformations: Clinical and pathological findings in 11 patients

Marieke Oostvogels, Lorine B. Meijer-Jorna, Allard C. Van Der Wal, Charlène E.U. Oduber, Oren Lapid, Chantal M.A.M. Van Der Horst

Research output: Contribution to journalArticlepeer-review

Abstract

Hypertrophy in capillary malformation (CM) may be present at birth or manifest itself later in life. To gain insight into the pathology of hypertrophic CM, we investigated a series of 11 excisional biopsies of hypertrophic lips. All biopsies showed dilated thin-walled microvessels in the superficial dermis without a neural component. However, large multinodular conglomerates of thick-walled vessels with a substantial increase in nerve fibers were found in the deeper parts of the lesions. These veins extended deep into the facial musculature. Hypertrophy in CM is caused by venous malformation underlying the CM. So CM associated with hypertrophy should be considered as Capillary Venous malformations.

Original languageEnglish
Pages (from-to)351-354
Number of pages4
JournalAnnals of Plastic Surgery
Volume72
Issue number3
DOIs
StatePublished - 1 Jan 2014
Externally publishedYes

Keywords

  • Capillary malformations
  • Histology
  • Hypertrophy
  • Surgery
  • Vascular malformations
  • Venous malformations

Fingerprint

Dive into the research topics of 'Hypertrophy in labial capillary malformations: Clinical and pathological findings in 11 patients'. Together they form a unique fingerprint.

Cite this