TY - JOUR
T1 - Hypertrophy in labial capillary malformations
T2 - Clinical and pathological findings in 11 patients
AU - Oostvogels, Marieke
AU - Meijer-Jorna, Lorine B.
AU - Van Der Wal, Allard C.
AU - Oduber, Charlène E.U.
AU - Lapid, Oren
AU - Van Der Horst, Chantal M.A.M.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Hypertrophy in capillary malformation (CM) may be present at birth or manifest itself later in life. To gain insight into the pathology of hypertrophic CM, we investigated a series of 11 excisional biopsies of hypertrophic lips. All biopsies showed dilated thin-walled microvessels in the superficial dermis without a neural component. However, large multinodular conglomerates of thick-walled vessels with a substantial increase in nerve fibers were found in the deeper parts of the lesions. These veins extended deep into the facial musculature. Hypertrophy in CM is caused by venous malformation underlying the CM. So CM associated with hypertrophy should be considered as Capillary Venous malformations.
AB - Hypertrophy in capillary malformation (CM) may be present at birth or manifest itself later in life. To gain insight into the pathology of hypertrophic CM, we investigated a series of 11 excisional biopsies of hypertrophic lips. All biopsies showed dilated thin-walled microvessels in the superficial dermis without a neural component. However, large multinodular conglomerates of thick-walled vessels with a substantial increase in nerve fibers were found in the deeper parts of the lesions. These veins extended deep into the facial musculature. Hypertrophy in CM is caused by venous malformation underlying the CM. So CM associated with hypertrophy should be considered as Capillary Venous malformations.
KW - Capillary malformations
KW - Histology
KW - Hypertrophy
KW - Surgery
KW - Vascular malformations
KW - Venous malformations
UR - http://www.scopus.com/inward/record.url?scp=84899928717&partnerID=8YFLogxK
U2 - 10.1097/SAP.0b013e31826053e9
DO - 10.1097/SAP.0b013e31826053e9
M3 - Article
C2 - 24051471
AN - SCOPUS:84899928717
SN - 0148-7043
VL - 72
SP - 351
EP - 354
JO - Annals of Plastic Surgery
JF - Annals of Plastic Surgery
IS - 3
ER -