Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp. in rats

Irit Dvir; Aliza Hannah Stark; Reuven Chayoth; Zecharia Madar; Shoshana Malis Arad

doi:10.3390/nu1020156

Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp. in rats

Irit Dvir, Aliza Hannah Stark, Reuven Chayoth, Zecharia Madar, Shoshana Malis Arad

Research output: Contribution to journal › Article › peer-review

92 Scopus citations

Abstract

Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.

Original language	English
Pages (from-to)	156-167
Number of pages	12
Journal	Nutrients
Volume	1
Issue number	2
DOIs	https://doi.org/10.3390/nu1020156
State	Published - 1 Jan 2009

Keywords

Dietary fiber
Foodomics
Hypocholesterolemic agents
Nutraceuticals
Red microalgae

ASJC Scopus subject areas

Food Science
Nutrition and Dietetics

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10.3390/nu1020156

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title = "Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp. in rats",

abstract = "Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.",

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AU - Arad, Shoshana Malis

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AB - Red microalgae contain functional sulfated polysaccharides (containing dietary fibers), polyunsaturated fatty acids, zeaxanthin, vitamins, minerals, and proteins. Studies in rat models support the therapeutic properties of algal biomass and isolated polysaccharides. Algal products incorporated into rat diets were found to significantly improve total serum cholesterol, serum triglycerides, hepatic cholesterol levels, HDL/LDL ratios and increased fecal excretion of neutral sterols and bile acids. Morphological and metabolic changes were induced by consumption of algal products. These results suggest that red microalgae can be used as potent hypocholesterolemic agents, and they support the potential use of red microalgae as novel nutraceuticals.

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Hypocholesterolemic effects of nutraceuticals produced from the red microalga Porphyridium sp. in rats

Abstract

Keywords

ASJC Scopus subject areas

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