Identification of heroin in street doses using 1D-TOCSY nuclear magnetic resonance

N. Suryaprakash, M. Azoury, Z. Goren, R. Jelinek

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Heroin street doses are complex mixtures commonly analyzed in forensic laboratories. Identification of the illicit substance in these street doses is among the primary analytical tasks of a forensic laboratory. We demonstrate that the one-dimensional 1D-TOCSY NMR experiment permits identification of heroin in standard mixtures containing up to ten or more different components. This method produces an easily-identified and effective 'fingerprint' for heroin within a mixture of other substances. The method has been successfully tested as a tool for identification of heroin in street doses from police casework in Israel. This NMR technique is robust and quick (a measurement can be carried out in 10-15 min), and it does not require any preliminary physical or chemical treatments of the sample to be examined, due to the effective spectroscopic 'filtering' of the interfering components. The 1D-TOCSY NMR method can potentially be used in combination with additional analytical methods as a routine tool in forensic laboratories to positively identify heroin for court purposes.

Original languageEnglish
Pages (from-to)963-967
Number of pages5
JournalJournal of Forensic Sciences
Issue number5
StatePublished - 1 Jan 2000


  • Forensic science
  • Heroin
  • Identification
  • Nuclear magnetic resonance
  • Street doses

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Genetics


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