Identifying p53 Target Genes Using Hypomorphic Variants

Bibek Bhatta, Tomer Cooks

Research output: Contribution to journalEditorial


SUMMARY: The reduced tumor suppression activity of hypomorphic variants of the TP53 gene was used by Indeglia and colleagues to corroborate PADI4 as a p53 target. The study makes a noteworthy advancement in comprehending the downstream implications of TP53-PDI4, including potential predictions of survival and the efficacy of immunotherapy. See related article by Indeglia et al., p. 1696 (4).

Original languageEnglish
Pages (from-to)1518-1520
Number of pages3
JournalCancer Discovery
Issue number7
StatePublished - 7 Jul 2023

ASJC Scopus subject areas

  • Oncology


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