TY - JOUR
T1 - Immunologic alterations in xeroderma pigmentosum patients
AU - Wysenbeek, Arjeh J.
AU - Weiss, Haya
AU - Duczyminer‐Kahana, Malka
AU - Grunwald, Marcello H.
AU - Pick, Albert I.
PY - 1986/1/1
Y1 - 1986/1/1
N2 - Nine xeroderma pigmentosum (XP) patients were investigated. In comparison to a normal control group the XP patients had a reduced OKT‐4 lymphocyte subpopulation, reduced response of lymphocytes to phytohemagglutinin in autologous serum, and diminished delayed hypersensitivity skin reaction. The possible contribution of ultraviolet irradiation to the observed immunologic alterations, and the link of these alterations to the susceptibility of patients for malignant transformation is discussed. Cancer 58:219–221, 1986.
AB - Nine xeroderma pigmentosum (XP) patients were investigated. In comparison to a normal control group the XP patients had a reduced OKT‐4 lymphocyte subpopulation, reduced response of lymphocytes to phytohemagglutinin in autologous serum, and diminished delayed hypersensitivity skin reaction. The possible contribution of ultraviolet irradiation to the observed immunologic alterations, and the link of these alterations to the susceptibility of patients for malignant transformation is discussed. Cancer 58:219–221, 1986.
UR - http://www.scopus.com/inward/record.url?scp=0022455776&partnerID=8YFLogxK
U2 - 10.1002/1097-0142(19860715)58:2<219::AID-CNCR2820580203>3.0.CO;2-A
DO - 10.1002/1097-0142(19860715)58:2<219::AID-CNCR2820580203>3.0.CO;2-A
M3 - Article
AN - SCOPUS:0022455776
SN - 0008-543X
VL - 58
SP - 219
EP - 221
JO - Cancer
JF - Cancer
IS - 2
ER -
