Immunologic alterations in xeroderma pigmentosum patients

Arjeh J. Wysenbeek, Haya Weiss, Malka Duczyminer‐Kahana, Marcello H. Grunwald, Albert I. Pick

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


Nine xeroderma pigmentosum (XP) patients were investigated. In comparison to a normal control group the XP patients had a reduced OKT‐4 lymphocyte subpopulation, reduced response of lymphocytes to phytohemagglutinin in autologous serum, and diminished delayed hypersensitivity skin reaction. The possible contribution of ultraviolet irradiation to the observed immunologic alterations, and the link of these alterations to the susceptibility of patients for malignant transformation is discussed. Cancer 58:219–221, 1986.

Original languageEnglish
Pages (from-to)219-221
Number of pages3
Issue number2
StatePublished - 1 Jan 1986
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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