Immunological abnormalities in opsoclonus cerebellopathy

Y. Herishanu, R. Apte, O. Kuperman

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Opsoclonus and other cerebellar symptomatology developed in a patient who underwent mastectomy for adenocarcinoma of the breast. No evidence for metastases was found. Immunological studies demonstrated decreased function of T suppressor cells and hyperreactivity of T helper cells in spite of a normal suppressor/ helper ratio. The clinical condition, as well as the immunological abnormalities normalized under steroid treatment. An autoimmune process as etiopathogenesis of this paraneoplastic syndrome is proposed.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalNeuro-Ophthalmology
Volume5
Issue number4
DOIs
StatePublished - 1 Jan 1985

Keywords

  • Cerebellum
  • Immunological aspects
  • Opsoclonus
  • Paraneoplastic syndrome

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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