Immunomodulation for treatment and prevention of atherosclerosis

Yaniv Sherer, Yehuda Shoenfeld

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations


In recent years, it has become clear that the immune system has a major role in atherosclerosis development and progression. More specifically, atherosclerosis fulfills all four criteria to define a condition as being an autoimmune in nature. This association also suggests that modification of the immune response in atherosclerosis could affect this process. In this review, we summarize different aspects of immunomodulation in atherosclerosis. These include immunosuppression, active immunization, induction of tolerance, administration of intravenous immunoglobulin, gene therapy, cytokine network manipulation and statins.

Original languageEnglish
Pages (from-to)21-27
Number of pages7
JournalAutoimmunity Reviews
Issue number1-2
StatePublished - 1 Feb 2002
Externally publishedYes


  • Atherosclerosis
  • Autoimmunity
  • Cytokine
  • Gene therapy
  • Immunization
  • Immunomodulation


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