Immunomodulation of various autoimmune diseases by intravenous immunoglobulin

Yaniv Sherer; Yair Levy; Fabrizzio Fabrizzi; Yehuda Shoenfeld

doi:10.1358/dot.1999.35.7.548264

Immunomodulation of various autoimmune diseases by intravenous immunoglobulin

Yaniv Sherer, Yair Levy, Fabrizzio Fabrizzi, Yehuda Shoenfeld

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

Intravenous immunoglobulin (IVIg) is currently an accepted treatment for some autoimmune diseases and it has recently been used empirically in various other autoimmune conditions. This review discusses the role of IVIg in autoimmunity, mainly in systemic lupus erythematosus and systemic vasculitis. Clinical experience with IVIg, as well as its mechanisms of action with special emphasis on modulation of the idiotypic network, are also presented.

Original language	English
Pages (from-to)	513-518
Number of pages	6
Journal	Drugs of Today
Volume	35
Issue number	7
DOIs	https://doi.org/10.1358/dot.1999.35.7.548264
State	Published - 1 Jan 1999
Externally published	Yes

ASJC Scopus subject areas

Medicine (all)

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10.1358/dot.1999.35.7.548264

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title = "Immunomodulation of various autoimmune diseases by intravenous immunoglobulin",

abstract = "Intravenous immunoglobulin (IVIg) is currently an accepted treatment for some autoimmune diseases and it has recently been used empirically in various other autoimmune conditions. This review discusses the role of IVIg in autoimmunity, mainly in systemic lupus erythematosus and systemic vasculitis. Clinical experience with IVIg, as well as its mechanisms of action with special emphasis on modulation of the idiotypic network, are also presented.",

author = "Yaniv Sherer and Yair Levy and Fabrizzio Fabrizzi and Yehuda Shoenfeld",

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AU - Sherer, Yaniv

AU - Levy, Yair

AU - Fabrizzi, Fabrizzio

AU - Shoenfeld, Yehuda

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Y1 - 1999/1/1

N2 - Intravenous immunoglobulin (IVIg) is currently an accepted treatment for some autoimmune diseases and it has recently been used empirically in various other autoimmune conditions. This review discusses the role of IVIg in autoimmunity, mainly in systemic lupus erythematosus and systemic vasculitis. Clinical experience with IVIg, as well as its mechanisms of action with special emphasis on modulation of the idiotypic network, are also presented.

AB - Intravenous immunoglobulin (IVIg) is currently an accepted treatment for some autoimmune diseases and it has recently been used empirically in various other autoimmune conditions. This review discusses the role of IVIg in autoimmunity, mainly in systemic lupus erythematosus and systemic vasculitis. Clinical experience with IVIg, as well as its mechanisms of action with special emphasis on modulation of the idiotypic network, are also presented.

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DO - 10.1358/dot.1999.35.7.548264

M3 - Review article

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Immunomodulation of various autoimmune diseases by intravenous immunoglobulin

Abstract

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