Immunomodulation of various autoimmune diseases by intravenous immunoglobulin

Yaniv Sherer, Yair Levy, Fabrizzio Fabrizzi, Yehuda Shoenfeld

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Intravenous immunoglobulin (IVIg) is currently an accepted treatment for some autoimmune diseases and it has recently been used empirically in various other autoimmune conditions. This review discusses the role of IVIg in autoimmunity, mainly in systemic lupus erythematosus and systemic vasculitis. Clinical experience with IVIg, as well as its mechanisms of action with special emphasis on modulation of the idiotypic network, are also presented.

Original languageEnglish
Pages (from-to)513-518
Number of pages6
JournalDrugs of Today
Issue number7
StatePublished - 1 Jan 1999
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (all)


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