Impaired mechanical response of an EDMD mutation leads to motility phenotypes that are repaired by loss of prenylation

Keyphrases

• Mechanical Response 100%
• Motility 100%
• Prenylation 100%
• Emery-Dreifuss muscular Dystrophy 100%
• Lamin 60%
• Caenorhabditis Elegans 40%
• Mechanical Model 40%
• Mechanical Properties 20%
• Mechanical Strain 20%
• Future Therapeutics 20%
• Therapeutic Approaches 20%
• Disease-associated 20%
• Cell Death 20%
• Autosomal Dominant Disorder 20%
• Experimental Protocol 20%
• Muscle Phenotype 20%
• Lamin C 20%
• LINC Complex 20%
• Emerin 20%

Biochemistry, Genetics and Molecular Biology

• Lamin 100%
• Prenylation 100%
• Caenorhabditis Elegans 50%
• Cell Death 25%
• Autosomal Dominant Inheritance 25%
• Emerin 25%
• LINC Complex 25%

Neuroscience

• Muscular Dystrophy 100%
• Prenylation 100%
• Lamin 60%
• Cell Death 20%
• Caenorhabditis Elegans 20%
• Emerin 20%
• Lamin A 20%